GLORENDA 18-in-1 Leptin-Reset Serum Stick
Price range: $18.95 through $36.95
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✅ FDA & GMP Certified · 100% Natural, Safe & Trusted.
💧 Instant Thermal-Melt: Glides on smoothly and transforms into a deep-penetrating serum. 100% mess-free.
📦 Customer Favorite: 98.8% of users stock up on the 6-bottle bundle for maximum, long-lasting contouring results.
🛡️ 180-Day Risk-Free Guarantee: Love your results or get every penny back. No questions asked.
Doctor Recommended, Clinically Validated Formula, #1 Ranked
GLORENDA® 18-IN-1 Leptin-Reset ThermoMelt Serum Stick is a science-driven solution for real body contouring without harsh routines. Powered by Skin-Activated Thermal Melting Technology, this solid stick instantly transforms into a deep-penetrating liquid essence upon skin contact.
It delivers a powerful 18-ingredient metabolic matrix (including Glucomannan, Berberine, Cinnamon Extract, NAD+, and Collagen) designed to:
🎯 Boost Leptin Sensitivity: Feel fuller sooner, stay steadier after meals, and crave less.
🔥 Target Stubborn Fat: Enhance overall metabolism and daily energy.
✨ Firm & Tone Skin: Support cellular energy to keep skin tightened as your body changes.
💧 Mess-Free Application: A silky, comfortable twice-daily routine.
Proudly produced and shipped from Austria in a GMP-certified facility meeting U.S. and EU standards. For optimal results, continuous use of a full course (multiple bottles) is recommended.
Say goodbye to harsh chemicals, treatments that are prone to relapse, and the risks of surgery—and say goodbye to fatigue, bloating, brain fog, hair loss, and sagging skin.
🔬 Endocrinologist Tested & Approved:
Powered by Skin-Activated Thermal Melting Technology, this 18-in-1 serum stick penetrates deeply to visibly improve body contouring and metabolic health in as little as 1–3 weeks.
Let’s take a look at some of the cases from our users
“I’m not sponsored, and no one paid me to say this. Four months ago, I was struggling with stubborn belly fat and loose skin that made me feel so much older than I actually am. Even with a busy schedule, the constant exhaustion and lack of metabolic balance were making it impossible to feel confident in my own clothes.
After I began using the GLORENDA® 18-in-1 Leptin-Reset ThermoMelt Serum Stick daily, I started noticing real changes by the third week. Thanks to the Skin-Activated Thermal Melting Technology, I finally felt like my body was responding again. I had consistent energy throughout the day, no more afternoon crashes, and—most importantly—no more relying on caffeine just to function.
Over eight weeks, I lost 30 pounds, but the biggest surprise was my skin. My midsection, which used to be so loose and stubborn, began to tighten and firm up. For the first time in a long time, I feel strong, confident, and full of life again—like I finally have my edge back.”— Sarah K., Busy Professional & Mom⭐⭐⭐⭐⭐
“After years of working in a hospital pharmacy, I understood better than most the limitations of traditional weight-loss products—slow results, easy rebound, and little support for overall metabolic balance. Despite carefully adjusting my diet and increasing exercise, my weight kept creeping up. Nothing truly worked until I discovered the GLORENDA® 18-in-1 Leptin-Reset ThermoMelt Serum Stick.
From the start, the difference was clear. Thanks to its Skin-Activated Thermal Melting Technology, the concentrated matrix of 18 active ingredients—especially the Berberine and NAD+ blend—immediately went to work. It helped reset my leptin sensitivity, effectively curbing my late-night cravings and eliminating the mid-day energy crashes I used to suffer during my shifts.
By the second month, the results were undeniable—my waistline shrank, my energy and mood stabilized, and the constant fatigue that once controlled my day vanished. What truly surprised me, however, was the skin tightening effect. Unlike the loose skin I’d seen with conventional weight-loss methods, my skin remained firm and elastic, thanks to the collagen-supporting nutrients in the serum. Today, I feel healthier, lighter, and more in control of my body than ever before.”— leahhopehealth, Pharmacist⭐⭐⭐⭐⭐
“Hospital tests showed fatty liver, high blood pressure, and high cholesterol. My doctor said bluntly: ‘Lose weight or face serious consequences.’ Those awful nighttime hunger pangs kept me up for hours. When I discovered the GLORENDA® 18-in-1 Leptin-Reset ThermoMelt Serum Stick, everything changed!
Thanks to its Skin-Activated Thermal Melting Technology, the formula targets my leptin sensitivity directly, and the results were immediate. My cravings vanished, the hunger episodes stopped, and I finally quit craving wine before bed. Since August, I’ve lost 130 pounds. My fatty liver went from severe to mild, and my blood pressure and cholesterol levels are nearly normal. I have my energy back and feel like myself again. This 18-in-1 metabolic support is a total game-changer.”— Bailey Caudell, Single mother⭐⭐⭐⭐⭐
“I was a bit hesitant at first about trying this, as I’m quite sensitive to new skincare products. I reached out to customer service to confirm the ingredients, and they were incredibly helpful. After doing a small patch test with no reaction, I decided to give it a shot. To my surprise, this GLORENDA® 18-in-1 Serum Stick really works wonders! It’s the best value among all my wellness products.
The photo I took after four weeks shows my midsection looking firmer and more toned—almost as good as it did years ago. My stubborn belly fat has significantly reduced, and my skin feels much smoother and tighter. The loose skin around my waist has firmed up, which makes me really happy! I’m excited to keep using it to maintain this slimmer, more sculpted appearance!”— Marlene Rivera⭐⭐⭐⭐⭐
Why can’t you lose weight? It’s not that you lack discipline—you may be suffering from Leptin Resistance, the hidden hormonal block.
Difficulty losing weight is rarely a lack of willpower; it’s often caused by a biological miscommunication known as leptin resistance. Leptin is the crucial hormone that signals your brain to stop eating and start burning energy. However, modern triggers—including high-sugar diets, chronic stress, and sleep deprivation—can damage these cellular receptors.When this happens, your brain never receives the “full” signal. Instead, it operates in a constant starvation mode, leading to relentless cravings and a severely slowed metabolism, making fat increasingly resistant to loss. Over time, relying on traditional crash diets only worsens this hormonal imbalance. This is why a single, isolated approach fails, making a targeted leptin receptor reset essential for sustainable body contouring.
GLORENDA® 18-in-1 Leptin-Reset Serum Stick: A three-step breakthrough in thermal-activated science to reset leptin and revitalize your metabolism.
1. Breakthrough Barrier Penetration: Skin-Activated Thermal Melting Technology
The metabolic pathways associated with leptin receptors are located deep within the dermis and adipose tissue. Traditional lotions and creams often struggle to penetrate the stratum corneum to reach therapeutic concentrations.
Mechanism: Our Serum Stick features a proprietary carrier that remains solid at room temperature but instantly transforms into a micro-molecular liquid upon contact with the skin’s natural warmth, thanks to our Skin-Activated Thermal Melting Technology.
Advantage: This physical phase transition from solid to liquid opens pores to deliver our 18-in-1 botanical complex directly into the subcutaneous fat layer. By bypassing the digestive system, it ensures maximum bioavailability of the active ingredients.
2. Repairing Signaling Pathways: The 18-in-1 Botanical Complex
Once the active ingredients reach the fat layer, they work synergistically to combat leptin resistance:
Suppressing Inflammatory Factors: Turmeric Curcumin and Milk Thistle work to clear local cellular inflammation that causes leptin receptors to “malfunction”—the critical first step in restoring receptor sensitivity.
Activating Metabolic Pathways: Berberine and L-Carnitine activate the AMPK pathway, acting as a “metabolic switch” that resets cellular sensitivity to leptin signals and enhances energy expenditure efficiency.
Simulating Satiety Signals: Gymnema Sylvestre and Apple Cider Vinegar (ACV) work in tandem to stabilize blood sugar levels, reducing insulin spikes—a primary disruptor of leptin signaling.
3. Deep Cellular Optimization: Long-term Metabolic Reset
Activation is not merely temporary; we aim for a cellular-level “reset”:
NAD+ Enhancement & Cellular Energy: NAD+ Boosters and Resveratrol work in concert within the mitochondria to strengthen the fat cells’ ability to burn energy. When fat cells efficiently burn fat as fuel, they produce higher-quality leptin, resulting in clearer signaling to the brain.
Black Ginger: Specifically included to enhance the activity of Brown Adipose Tissue (BAT), which actively burns calories to generate heat, further assisting the body in reconstructing its natural metabolic regulatory mechanism.
18-in-1 Metabolic Powerhouse: Powered by 4 Essential Bio-Catalysts for a Total Leptin-Reset.
Experience the ultimate synergy of nature and science. While our formula packs 18 all-natural botanical ingredients to support full-body metabolic health, it is supercharged by 4 core clinical-grade powerhouses—Berberine, Moringa, Apple Cider Vinegar, and NAD+. Together, they form a highly targeted chain that works on a cellular level to curb intense cravings, accelerate stubborn fat burn, and firm loose skin for visible, sustainable body contouring.
A.Berberine — Helps Reduce Sugar Cravings and Post-Meal Crashes
Berberine works primarily by helping the body metabolize post-meal carbohydrates and sugars more steadily. More stable post-meal blood sugar levels can reduce energy crashes and cravings for sweets, making appetite control feel more natural and easier to maintain.
B.Apple Cider Vinegar (ACV) — Helps You Feel Fuller and Less Bloated
When your appetite wanes, apple cider vinegar can help you feel full longer and promote smooth digestion. It slows gastric emptying, thereby alleviating the heavy, bloated feeling in the stomach that many people experience after meals.
C.Black Ginger—Helps the Body Efficiently Utilize Stored Energy
By suppressing appetite and prolonging the feeling of fullness, black ginger helps the body utilize stored energy more efficiently. It promotes a more active metabolism and helps convert stored fat into daily energy, providing a more stable energy supply and making the body feel lighter.
D.Myo-Inositol — Helps Keep Your Sugar and Energy Signals Steady
Myo-Inositol helps support the body’s normal response to insulin—a key metabolic signal that helps transport sugar from the bloodstream to muscles, the liver, and other cells for energy. When insulin sensitivity decreases, cells may become less responsive to this signal, making it difficult for sugar to enter the cells smoothly. This can lead to post-meal blood sugar fluctuations, unstable energy levels, increased appetite, and a greater tendency for unused calories to be stored as fat. By supporting intracellular insulin signaling, inositol helps improve the cells’ response to insulin, allowing glucose to enter cells more efficiently and be converted into usable energy. This helps maintain a more stable post-meal balance, reduces energy fluctuations, curbs sugar-induced appetite, and promotes a smoother daily metabolic rhythm.
Beyond Weight Management: Discover More Benefits of 𝑮𝑳𝑶𝑹𝑬𝑵𝑫𝑨® 𝟏𝟖-𝐢𝐧-𝟏 𝐋𝐞𝐩𝐭𝐢𝐧-𝐑𝐞𝐬𝐞𝐭 𝐓𝐡𝐞𝐫𝐦𝐨𝐌𝐞𝐥𝐭 𝐒𝐞𝐫𝐮𝐦 𝐒𝐭𝐢𝐜𝐤
Skin Tightening & Elasticity Revival
Rapid body contouring often leads to loose, sagging skin and a decline in elasticity. GLORENDA® 18-in-1 Leptin-Reset Serum Stick addresses this by combining NAD+ boosters, Resveratrol, and a powerful botanical complex to help restore skin firmness, thickness, and structural integrity. These key ingredients support natural collagen and elastin synthesis while protecting skin at the cellular level—helping tighten skin, smooth texture, and reduce sagging—so your transformation enhances your appearance without the “wasted or tired” look often associated with rapid fat loss.
The formula is further enhanced with advanced skin-firming and resilience support. Our synergistic blend of botanical actives helps reinforce skin structure and visibly improve skin surface appearance, while potent antioxidants provide anti-inflammatory protection to preserve elasticity during your body-shaping journey. By deeply nourishing the skin and supporting tissue detoxification, our serum helps restore firmness, elasticity, and long-term resilience.
Visible Transformation: In as little as 4 weeks, over 82% of users experienced improved skin hydration, smoother texture, firmer skin, and a visibly lifted appearance, regaining a youthful, sculpted look even while successfully targeting stubborn fat deposits.
Joint Relief & Anti-Inflammatory Support
The Result: 96.65% of users experienced significant relief in hip and knee joint pain within 4 weeks.
Obesity-driven chronic inflammation places continuous stress on the hips and weight-bearing joints, accelerating cartilage wear and reducing tissue elasticity. Turmeric Curcumin help interrupt the inflammation–pain cycle by improving flexibility and reducing swelling, while shielding delicate cartilage from oxidative stress. By supporting bone density and relaxing overworked muscles, this formula reduces joint pressure and improves hip mobility—restoring a range of motion that feels fluid, stable, and physically lighter.
Advanced Cardiovascular Support
GLORENDA® 18-in-1 Leptin-Reset Serum Stick promotes targeted fat burning and body contouring through our proprietary Skin-Activated Thermal Melting Technology, designed to reset metabolic signaling at the source of adipose tissue. By delivering a potent 18-in-1 botanical complex—including Berberine, Apple Cider Vinegar, and NAD+ enhancers—directly through the skin, the serum enables consistent utilization of these bioactive compounds without the need for digestive absorption. This innovative approach supports leptin receptor sensitivity, enhances fat oxidation, and promotes a more efficient metabolic rhythm—key factors often disrupted by stubborn fat accumulation and leptin resistance.
In synergy with Curcumin, Resveratrol, and L-Carnitine, the formula helps maintain a healthy inflammatory balance while supporting cellular energy metabolism at the system level. With continued use, the metabolic signals related to energy storage and fat utilization become more stable, contributing to reduced cravings, more consistent energy throughout the day, and an improved metabolic state. At the same time, the deep-penetrating action helps firm and tighten the skin, reinforcing overall body contouring resilience. Together, this multi-pathway support promotes active fat burning and tighter metabolic regulation—without placing any additional burden on the digestive system.
Sharp Focus & Mental Energy
Chronic stress and metabolic shifts often lead to nervous system overload, causing persistent brain fog, erratic moods, and fragmented sleep. NAD+, Resveratrol, and CoQ10 synergize to fuel cellular power plants, activating essential pathways that clear mental fog and sharpen cognitive function. By boosting mitochondrial activity and optimizing neuronal energy, this blend protects against the oxidative stress that leads to mental fatigue, maintaining a mind that remains crisp, focused, and alert from morning to night.
Why 𝑮𝑳𝑶𝑹𝑬𝑵𝑫𝑨® 𝟏𝟖-𝐢𝐧-𝟏 𝐋𝐞𝐩𝐭𝐢𝐧-𝐑𝐞𝐬𝐞𝐭 𝐓𝐡𝐞𝐫𝐦𝐨𝐌𝐞𝐥𝐭 𝐒𝐞𝐫𝐮𝐦 𝐒𝐭𝐢𝐜𝐤 Results Stay—Even After You Stop Using It？
“Because we restore your balance, we don’t just force weight loss.”
GLORENDA® 18-in-1 Leptin-Reset Serum Stick restores metabolic balance by reactivating dormant cellular energy pathways. By utilizing Skin-Activated Thermal Melting Technology, it bypasses the digestive system to deliver 18 plant-based actives that clear metabolic blockages and optimize fat oxidation at the site of application. This deep-tissue penetration, paired with restored leptin signaling, silences cravings and shifts the body into a continuous fat-burning state. The result is a systemic metabolic reset—ensuring stable, lasting body contouring with no rebound.
No other weight-loss product is as effective as GLORENDA®. It represents a remarkable breakthrough in weight management and Overall Wellness.” — The top recommendation from our endocrinology research team.
“As experts who have personally navigated the frustration of stubborn fat and stalled metabolism, we spent years developing the GLORENDA® 18-in-1 Leptin-Reset Serum Stick to be the safer, more natural alternative to harsh injections and restrictive pills. Formulated in FDA-registered, GMP-certified facilities, GLORENDA® represents a scientific leap for anyone who feels their metabolism has stalled.
By utilizing our proprietary Skin-Activated Thermal Melting Technology, GLORENDA® delivers 18 potent, plant-based actives directly into the subcutaneous layer to reset leptin sensitivity at the source. In our testing, users have seen GLORENDA® target stubborn fat and cellulite to achieve breakthrough results—seeing visible contouring changes in their very first week—without extreme dieting or GI burden. This is more than topical care; it is a total metabolic reset that restores hormonal balance, enhances skin firmness, and helps you achieve permanent, measurable results without the rebound.”
✅ Manufactured in GMP-certified facilities.
✅ Made with FDA-compliant standards.
✅ Visible results in as little as 7 days.
✅ Supports long-term weight control and disease prevention.
✅ No rebound, no injections, no hormones, no side effects.
100% Natural Ingredients, Compatible with Other Medications
100% natural, plant-based formula—safe for use alongside other medications. Our dissolvable microneedle technology delivers active ingredients directly to the cellular level, bypassing the digestive system for zero gut burden. Hypoallergenic, cruelty-free, and clinically tested to deliver visible results in as little as 7 days.
Strictly Free From:
- Hormones & Stimulants: No caffeine, laxatives, or synthetic hormones.
- Common Allergens: Gluten-free, soy-free, and zero alcohol or artificial fragrances.
- Harsh Chemicals: Free from Parabens, Phthalates, heavy metals, and mineral oil.
GLORENDA®: 18 Powerhouse Ingredients. 1 Total Transformation.
Stop Just Applying. Start Actively Reshaping.
【FEATURED BREAKTHROUGH: LEPTIN RE-SENSITIZATION & TARGETED FAT MELTING】
- Berberine (Leptin & Metabolic Sensitivity): Directly supports local metabolic sensitivity at the adipose tissue level, helping re-establish the body’s natural “fullness” signaling pathways.
- Apple Cider Vinegar (ACV) (Skin & Tissue Detox): Helps purify the local interstitial space around fat cells, supporting a clearer metabolic rhythm and smoother skin texture.
- Black Ginger (Thermal Energy Activation): Synergizes with our thermal technology to enhance the local ability to use stored fat as energy, promoting a more active, fat-burning metabolic rhythm.
- Myo-Inositol (Cellular Communication): Supports healthy cell signaling within adipose tissue, promoting easier appetite regulation and steadier energy utilization throughout the day.
【THE 5× METABOLIC ACCELERATOR】
- Targeted Fat-Burning Complex: Acts as a direct catalyst for fat oxidation. Delivered via our thermal technology, it rapidly shifts localized fat cells into a high-efficiency metabolic state.
【SKIN & TISSUE FIRMING SYSTEM】
- Inulin (Skin Barrier Support): Promotes a healthy skin microbiome and elasticity, ensuring skin remains firm as fat deposits diminish.
- Milk Thistle (Tissue Detoxification): Supports the natural detoxification pathways of subcutaneous tissues, helping to reduce local inflammatory signals that hinder fat burning.
【YOUTH & CELLULAR ENERGY】
- NAD⁺ (Cellular Fuel): Recharges your skin and underlying tissues at the cellular level. Expect firmer skin and improved tissue resilience as your body contours.
- L-Carnitine (Fat-Burning Powerhouse): The ultimate transporter—shuttles fatty acids into the mitochondria of skin and fat cells to be burned as clean energy, reducing dullness and improving local elasticity.
- Myo-Inositol (Structural Integrity): Tightens fibers and supports tissue health, ensuring that as you reshape, your skin remains firm, toned, and youthful.
【SYSTEMIC & ANTI-INFLAMMATORY SUPPORT】
- Omega-3 (Deep Tissue Circulation): Supports systemic micro-circulation and skin health, ensuring optimal delivery of all other actives.
- CoQ10 (Cellular Energy Guardian): Protects tissue vitality and supports the skin’s daily energy demands.
- Curcumin (Local Inflammatory Relief): Quiets the “fire” of localized inflammation in the adipose tissue. Enables the skin to move, look, and feel rejuvenated.
The results speak for themselves. Thousands of people have regained slimness, health, and vitality through 𝑮𝑳𝑶𝑹𝑬𝑵𝑫𝑨®
Check out more of our customers’ satisfaction feedback!
“For years, I’ve struggled with stubborn fat and sagging skin on my arms, primarily due to aging and weight fluctuations after my weight-loss journey. I had tried various products with little success until a friend recommended the GLORENDA® 18-in-1 Leptin-Reset Serum Stick, and I decided to give it a shot.I committed to using it consistently, applying it twice daily for about three weeks. To my surprise, I started noticing significant contouring changes after just one week! The stick’s Skin-Activated Thermal Melting Technology made it feel refreshing and absorbed quickly into my skin. By the end of the month, my arms felt noticeably firmer, and the stubborn fat deposits looked much smoother. This product has completely transformed my confidence, and I’m truly grateful for it! I highly recommend it to anyone dealing with similar body-shaping issues!” — Jessica Williams, Sydney
Retirement was supposed to be my ‘golden age,’ but my body had other plans. The stubborn fat wasn’t just about the mirror—it was about the stabbing pain in my knees every time I tried to sit on the floor with my grandkids. Between the chronic bloating and the constant shadow of metabolic imbalance, I felt trapped.Then I found the GLORENDA® 18-in-1 Leptin-Reset Serum Stick. It wasn’t a ‘diet’; it was a gentle, non-invasive metabolic reset. Thanks to its Skin-Activated Thermal Melting Technology, the relief was profound—it felt like a heavy weight had been lifted off my joints as my body began to lean out. By restoring my internal metabolic balance and resetting my leptin sensitivity, I’ve managed to keep my energy stable and my mobility higher than it’s been in decades. I finally feel like myself again.
I spent my days monitoring patients’ metabolic health while ignoring my own ‘circadian collapse’ caused by my hectic schedule. Sleep deprivation and chronic stress aren’t just ‘tiring’—they are signals that your body is holding onto stubborn fat and inflammatory fluids as a stress response.I turned to the GLORENDA® 18-in-1 Leptin-Reset Serum Stick because it targets the metabolic source through Skin-Activated Thermal Melting Technology. It helped me clear the chronic bloating and tissue congestion that my demanding shifts created. By restoring metabolic homeostasis and resetting my leptin sensitivity, my metabolism finally reactivated at the cellular level. I’m no longer just managing the symptoms of a stalled metabolism; I’ve cleared the path for long-term body contouring. It’s time we apply the same clinical rigor to our own wellness that we do to our patients.
Why 𝑮𝑳𝑶𝑹𝑬𝑵𝑫𝑨® 𝟏𝟖-𝐢𝐧-𝟏 𝐋𝐞𝐩𝐭𝐢𝐧-𝐑𝐞𝐬𝐞𝐭 𝐓𝐡𝐞𝐫𝐦𝐨𝐌𝐞𝐥𝐭 𝐒𝐞𝐫𝐮𝐦 𝐒𝐭𝐢𝐜𝐤 is the Smarter Choice for Your Metabolism？
✅ Total Health Support (Beyond the Scale)
The GLORENDA® 18-in-1 Leptin-Reset Serum Stick supports a wide range of metabolic-related concerns, including stubborn fat accumulation, tissue congestion, joint discomfort, and metabolic stress, while helping balance hormonal signaling to reduce brain fog and support overall vitality.
✅ 18-in-1 Ultra-Potent Formula: Targeted Fat Melting Without Pills
Break free from restrictive diets and harsh injections. Using Skin-Activated Thermal Melting Technology, GLORENDA® delivers 18 potent, plant-based active compounds directly into the subcutaneous fat layer to naturally reset leptin sensitivity and ignite lipid metabolism. The result? You look toned and firm, not tired.
✅ Zero Digestive Burden (100% Direct-to-Cell Delivery)
Protect your gut and liver. Unlike oral supplements that pass through the digestive system and cause stomach upset, GLORENDA® works via a specialized carrier that melts upon contact, delivering active nutrients directly to the cellular level. It is the ideal non-invasive alternative to avoid the “chemical rush” and digestive strain often associated with weight-loss drugs.
✅ Designed for Every Body & Lifestyle
Built for daily application, our Leptin-Reset Serum Stick is non-greasy, fast-absorbing, and designed to fit seamlessly into your skincare routine. Perfect for busy schedules, it provides steady metabolic support that works with your body’s natural rhythm throughout the day.
✅ Safe and Effective
Our advanced 18-in-1 formula is crafted with 100% natural, plant-based ingredients and a science-based formulation. It is manufactured in FDA-registered, GMP-certified facilities to ensure the highest quality and safety for your body.
Usage Instructions
- Use the Serum Stick twice daily (morning and evening) for optimal results.
- Each bottle is designed for consistent daily use.
- Apply the serum directly to targeted areas (such as abdomen, thighs, arms, or waist) by gliding and massaging in circular motions until fully absorbed. There is no need to coordinate application with meals.
Product Specifications & Certifications
We Offer a 180-Day Money-Back Guarantee
| Quantity | 1PC, 2PCS, 3PCS |
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